Abram Scientific

Less than 5-10 minutes

from insertion of sample (approx. 20 microliters) to

full viscoelastic curve and parameter generation

Low-cost, single-use diagnostic test strips that interface with a wireless, handheld meter that is vibration-insensitive

Mechanical viscoelasticity and density measurement for blood coagulation diagnostics

CoagCare / PLATFORM CAPABILITIES*

Thromboelastography
- Clot Formation Time
- Clot Stiffness (Fibrinogen)
- Platelet Activity
- Fibrinolysis
Thrombin Generation Assay
Direct Oral Anticoagulants (DOAC) Monitoring (including Factor IIa and Xa drug differentiation)
Prothrombin Time (PT) / International Normalized Ratio (INR)
Hematocrit (Hct)
Activated Partial Thromboplastin Time (aPTT)
Low- and High-range Activated Clotting Time (ACT)

* feasibility demonstrated on clinical & analytical blood samples

CoagCare

COVID-19

Coagulopathy is a major cause of death in COVID-19 patients

A high incidence of thromboembolic complications leading to organ-failure, stroke, pulmonary embolism (PE) and deep vein thrombosis (DVT) have been reported in asymptomatic, symptomatic, and recovering patient groups.
Coagulopathy plays a crucial role in the initial development of respiratory symptoms in COVID-19 patients and monitoring could predict disease progression.
Anticoagulation and transfusion therapies and monitoring are crucially needed both in inpatient and outpatient settings to ensure survival.

Viscoelastic tests can accurately detect and manage Coagulopathy

Consensus guidelines published by physicians and surgeons from the pandemic frontline in Wuhan specifically recommends the routine use of viscoelastic tests for diagnosing the type and extent of coagulopathy in COVID-19 patients.
Viscoelastic tests are increasingly being used as the ideal go-to-solution to screen for and accurately diagnose the hypercoagulable state observed in COVID-19 patients (i.e. by measuring clot stiffness & lysis) and enable goal-directed anticoagulation and blood transfusion management.

Critical need for fast, point-of-care (POC) viscoelastic tests to:

Quickly screen for coagulopathy in asymptomatic and symptomatic COVID-19 patients.
Provide closed-loop therapeutic management in ambulatory, inpatient and outpatient settings.